SPIRESPIRE VISION
Project Overview
SPIRE-VISION is a landmark collaborative project between SPIRE and the Department of Ophthalmology at Khyber Teaching Hospital (KTH), Peshawar. It focused on creating the first-ever comprehensive database of children born at less than 32 weeks gestation and screening them for Retinopathy of Prematurity (ROP) — a preventable condition that can cause blindness in preterm babies.
This groundbreaking effort, funded by USAID, was carried out under the leadership of Prof. Sadia Sethi and Dr. Nazli Gul, with Assoc. Prof. Dr. Imran Ahmad also playing a central role in the research.
Why This Project Matters
Silent Threat
Retinopathy of Prematurity (ROP) is a preventable cause of childhood blindness, yet often goes undetected in preterm infants.
High-Risk Population
Pakistan has one of the highest preterm birth rates in South Asia, leaving thousands of babies vulnerable each year.
Lack of Local Data
Until SPIRE-VISION, no structured registry existed in Pakistan to track ROP cases in premature newborns.
Global Relevance
Early detection and timely intervention can prevent lifelong disability, making this data crucial for neonatal care standards.
Implementation & Impact
Collaborative Screening Program
Implemented at the Department of Ophthalmology, Khyber Teaching Hospital (KTH), under the leadership of Prof. Sadia Sethi, Dr. Nazli Gul, and Dr. Imran Ahmad.
USAID-Funded Initiative
Supported by international funding, enabling advanced screening facilities and sustainable data collection.
First ROP Database in KPK
Established a comprehensive registry of infants born before 32 weeks gestation, creating a benchmark for neonatal eye health in the region.
Capacity Building
Strengthened the skills of ophthalmology teams in screening, documenting, and managing ROP cases.
Published Findings
Final report published in the Pakistan Journal of Medical Sciences, providing credible, peer-reviewed evidence for policymakers and practitioners.
Future Potential
This project sets the stage for expansion of neonatal eye screening programs across Pakistan, reducing preventable blindness in vulnerable populations.
Project Updates
Update 01
First ROP database successfully compiled at KTH, Peshawar.
Update 02
Update 03
SPIRE is exploring expansion of neonatal eye screening in other hospitals of KPK and beyond.
Collaboration Opportunities
SPIRE-VISION represents a major step forward in improving neonatal eye health in Pakistan. Future collaborations are welcome in:
How to Collaborate?
Review and sign the official SPIRE-VISION MOU
Future collaborations are welcome in:
Expanding neonatal screening programs
Building ROP registries across additional hospitals
Research and publications on child eye health
SPIRE VISION FAQs
What is SPIRE-VISION?
Why is this project important?
Who funded the project?
The project was funded by USAID and carried out in KTH’s Ophthalmology Department under the leadership of Prof. Sadia Sethi, Dr. Nazli Gul, and Dr. Imran Ahmad.
What were the outcomes of SPIRE-VISION?
- Creation of Pakistan’s first ROP screening database in Khyber Pakhtunkhwa.
- Publication of the final report in the Pakistan Journal of Medical Sciences.
- Training and capacity building for ophthalmology teams in neonatal screening.
How can researchers or institutions collaborate?
Where can I read the publication?
The final research article is available online: Exploring Retinopathy of Prematurity – ResearchGate Link
Partner With SPIRE in Child Eye Health
Join us in expanding neonatal eye screening and preventing childhood blindness in Pakistan. Together, we can protect vision and secure healthier futures for preterm babies.

